Precision Medicine with Personalised Care for Optimised Treatment.

Genetics is transforming modern healthcare by helping patients to understand how an individual's genetic makeup influences disease risk, diagnosis, treatment response and prevention.

The Department of Genetics at Kiran Multi Super Speciality Hospital provides comprehensive genetic counselling, genetic testing and genomic medicine services, working in collaboration with our super-speciality departments.

Our goal is to help patients and families receive the right information, the right test and the right clinical decision at the right time.

OUR KEY SERVICES

Genetic Counselling

Personalised genetic counselling for healthy individuals, patients and their families with:

• Suspected inherited disorders
• Family history of genetic disease
• Multiple affected family members
• Recurrent cancers or cancers at a young age
• Recurrent pregnancy loss or congenital abnormalities
• Developmental or unexplained medical conditions
• Concerns regarding inherited disease risk
• Genetic test interpretation and follow-up

Genetic Testing

We provide access to clinically appropriate genetic and genomic testing, including:

Hereditary/Germ Line Testing. Testing for identification of inherited genetic variants which result in the risk of diseases.

Cancer Genetics

• Hereditary cancer risk assessment
• Hereditary cancer gene panels
• Family/cascade testing where appropriate
• Genetic assessment for early-onset or multiple cancers
• Evaluation of familial cancer syndromes

Somatic / Tumour Genomic Testing

Genomic testing of tumour tissue or blood sample to help identify molecular alterations that will assist in treatment selection.

Pharmacogenomics

Where clinically appropriate, genetic information helps understand how an individual is likely to respond to certain medicines or experience adverse effects.

Rare Disease & Inherited Disorder Testing

Evaluation and testing for suspected genetic disorders according to clinical presentation and family history.

PRECISION ONCOLOGY

Integration of Genomics with Cancer Treatment

Cancer is not one disease. Different tumours can have different molecular characteristics.

Our genetic clinic works with oncology and other relevant specialities to support:

• Hereditary cancer risk assessment
• Germline genetic testing
• Tumour / somatic genomic testing
• Identification of potentially actionable molecular alterations
• Family risk assessment
• Cascade testing of eligible family members
• Genetic counselling before and after testing

Genomic information can complement clinical assessment and help the treating team make more informed decisions.

PRECISION MEDICINE

Treatment Tailored to the Individual

Genomic information provides additional insight into:

Disease → Genetic / Molecular Information → Clinical Interpretation → Personalised Management

Genetic testing is not appropriate for everyone. Our team helps determine which test is clinically relevant and how the result may influence patient management.

GENOMIC WELLNESS & RISK ASSESSMENT

Know Your Genetic Risk. Plan Your Health.

Genomic assessment helps identify individuals who have an increased inherited risk for selected conditions.

Cancer Risk

• Hereditary cancer syndromes
• Family history of cancer
• Early-onset cancers
• Multiple primary cancers
• Multiple affected relatives

Cardiovascular Risk

Genetic evaluation may be considered in selected patients with:

• Familial cardiovascular disease
• Suspected inherited cardiac disorders
• Unexplained sudden cardiac death in the family
• Suspected inherited cardiomyopathies or arrhythmias

Other Inherited Conditions

Genetic evaluation may be considered when clinical findings or family history suggest an inherited disorder.

WHO SHOULD CONSIDER A GENETIC CONSULTATION?

You may benefit from a genetic consultation if you or your family have:

• Cancer at a younger-than-usual age
• Multiple cancers in the same individual
• Two or more relatives with related cancers
• Cancer occurring across several generations
• A rare or unexplained disease
• A suspected inherited disorder
• A known genetic condition in the family
• A child with congenital abnormalities or unexplained developmental problems
• Recurrent pregnancy loss or suspected inherited reproductive/genetic conditions
• A strong family history of cardiovascular or other inherited disease
• A previously performed genetic test that needs expert interpretation

A genetic consultation does not necessarily mean that genetic testing will be recommended.

The decision to test should be based on the individual's clinical history, family history, examination and the potential clinical usefulness of the result.

GENETIC CONSULTATION: BEFORE & AFTER TESTING

Before testing, our genetic team discusses:

Why testing is being considered

• Possible benefits and limitations
• Appropriate test selection
• Possible outcomes
• Implications for family members
• Possible psychological and clinical considerations
• Informed consent

After Testing. Results are explained in the context of the patient's clinical and family history. Depending on the result, recommendations may include:

• Further clinical evaluation
• Disease-specific surveillance
• Preventive strategies
• Treatment-related discussion with the treating specialist
• Testing of appropriate family members
• Referral to relevant specialities
• Periodic follow-up

When Should You Refer a Patient to a Genetic Clinic?

Consider referral when there is:

1. Early-onset disease
2. Strong family history
3. Multiple affected relatives
4. Multiple primary cancers
5. Bilateral or unusual cancers
6. Suspected inherited syndrome
7. Rare or unexplained disease
8. Congenital abnormalities / developmental disorders
9. Suspected inherited cardiovascular disease
10. A need to interpret a previous genetic test

Simple Referral Pathway: -Identify → Refer → Genetic Counselling → Appropriate Test → Interpretation → Clinical Action → Family Assessment → Follow-up

FAMILY GENETICS & CASCADE TESTING

A genetic finding in one patient may have implications for other family members.

Where appropriate, our team can help identify relatives who may benefit from:

• Genetic counselling
• Targeted familial testing
• Risk assessment
• Appropriate surveillance
• Preventive healthcare planning

One diagnosis may help an entire family.

WHY CHOOSE OUR GENETIC CLINIC?

Clinical Genetics Expertise

Genetic testing is interpreted in the context of the patient's clinical and family history.

Integrated Super-Speciality Care

Genetic services are connected with the hospital's existing specialist departments.

Appropriate Test Selection

The objective is not simply to perform a genetic test but to select a test that is clinically appropriate and meaningful.

Family-Centred Care

Genetic information can sometimes provide valuable information for eligible family members.

Precision Medicine Approach

Genomic information is integrated with other clinical information to support personalised healthcare.

ONE CLINIC, MULTIPLE SPECIALITIES, ONE INTEGRATED APPROACH

Genomic medicine is increasingly relevant across multiple medical specialities. Our Department of Genetics works in collaboration with:

Medical Oncology | Surgical Oncology | Radiation Oncology | Cardiology | Neurology | Pediatrics | Obstetrics & Gynecology | Gastroenterology | Nephrology | Hematology | Endocrinology | Pulmonology | Dermatology | Ophthalmology | ENT | Orthopedics | Urology | General Medicine | and other super-specialties

This multidisciplinary approach helps integrate genetic information with the patient's clinical diagnosis, family history, imaging, pathology and treatment plan.

BOOK A GENETIC CONSULTATION

Take the First Step towards Personalised Healthcare

If you have a significant personal or family history of disease, a suspected inherited condition, or questions regarding genetic testing, consult our Department of Genetics.

Location – Kiran Hospital, 1st Floor, Cluster – G

Contact no.: 0261-7161183

Understanding your genes can help you understand your health — and make better-informed decisions for the future.